They used DCA (dichloroacetate) to do the inhibition. It's going to be ironic, if DCA will actually be useful for cancer treatment.
For those who don't know, DCA treatment made a lot of noise in the early 2000-s, with all kinds of conspiracy theories about it. Like drug companies covering it up because it "can't be patented". People even crowd-funded its clinical trials.
Unfortunately, it turned out to be too toxic on its own because cancer cells can adapt to the levels of DCA that kill the rest of the patient.
For those who don't know, DCA treatment made a lot of noise in the early 2000-s, with all kinds of conspiracy theories about it. Like drug companies covering it up because it "can't be patented". People even crowd-funded its clinical trials.
Unfortunately, it turned out to be too toxic on its own because cancer cells can adapt to the levels of DCA that kill the rest of the patient.