I got a student subscription to cursor and after giving it a good 6 hours I’ve abandoned it.
I extremely dislike the way it goes forth and bolts. I don’t trust these tools enough to just point it in the direction and say go, I like to be a human in the loop. Perhaps the use case I was working on then was difficult (quite old react native library upgrade across a medium sized codebase) but I eventually cracked this on Claude; cursor in both entropic and Gemini left me with an absolute mess.
Even repeatedly asking the prompt to keep me in the loop it kept on just running haywire.
The difficulty is stopping when control of the organism is actually achieved, not just when you ‘feel better’. Most people are totally unable to make this judgement
Huntingtons is not unique but certainly notable because it is caused by repeat sequences and therefore uniquely suited to mRNA silencing in this manner. There are very few other progressive (and I presume you also mean neurological) conditions, but also applied to the rest of the body, where this is the pathophysiology. For example, currently there is no immediate expansion of this to ie Parkinson’s (different pathophysiological basis) Lewy body (although maybe?) alzheimers (again possibly depending on whether it is tau, amyloid beta or simply ‘type 3 diabetes’) and nothing whatsoever for vascular dementia or ALS
Have a read (rather than guessing) - it’s fascinating! Your other reply has a good insight but on more of a related topic but the primary reason this exists is for error correction. So approx one third of single nucleotide mutations have no change on the expression of the DNA or protein. And some of those that do change the amino acid are actually conservative; ie changing a basic amino acid to another basic amino acid which may still end up folding in the same way
And in the US, a lot of the subsidies flow towards food that isn't edible without processing - soybeans and field corn as opposed to sweet corn.
Why? Because they've always grown it. So the subsidies encourage them to keep on growing it instead of diversifying into more competitive or higher value crops.
The subsidy is received by way of reduced insurance premiums. While that does make insurance affordable where it mightn't otherwise be, the rate of reduction is the same across all crops, so the insurance is made equally affordable no matter which crop you grow. Thus, for all intents and purposes, we can completely ignore the subsidy and simply focus on the insurance as that is ultimately what you are suggesting is significant. After all, if the subsidies were taken away, all it would really mean that you theoretically couldn't afford insurance anymore and would do without.
But what is significant about insurance? Since no good discussion is complete without a car analogy, let's go there. Say you always drove a truck. By your logic, auto insurance encourages you to keep driving trucks. Which suggests that if you could no longer get auto insurance, you would start driving a bus/van/car/whatever instead. But what makes you think that? If auto insurance disappeared for some reason, why wouldn't you still keep driving trucks as opposed to buses/vans/cars/whatever? There is probably a reason why you started driving trucks in the first place that doesn't go away even if insurance did.
In the case of corn and soybeans, there is a really good reason why they are grown so much: Because that's where the market is. It is what people want to buy. They are the most competitive and highest value crops in the regions they are grown.
> In the case of corn and soybeans, there is a really good reason why they are grown so much: Because that's where the market is. It is what people want to buy. They are the most competitive and highest value crops in the regions they are grown.
Given the fact that they're subsidised, I doubt that they're the most competitive crops. Competitive crops don't need to be subsidised.
Also, if they're so competitive, then why has the demolition of USAID caused them economic harm? A competitive product doesn't rely on a taxpayer subsidised buyer to make their market.
> Given the fact that they're subsidised, I doubt that they're the most competitive crops.
Every crop is subsidized.
> Competitive crops don't need to be subsidised.
Then no crop is competitive, so what is this alternative product that you are picturing? Stones? Who is going to buy those stones?
> then why has the demolition of USAID caused them economic harm?
John Deere's stock price is basically at its highest point ever. What economic harm are you talking about? When they are warning of imminent bankruptcy, then we can talk about there being economic harm. Some people sitting around complaining about something being different isn't real economic harm, just talk. Actions speak louder than words.
A lot of it also gets turned into biofuels or sent to third-world countries as food aid. That could easily be rerouted in a crisis scenario, if domestic food security became an issue.
The corn that gets turned into biofuel isn't edible without further processing into maize derived products, so in a crisis scenario, hope you can still highly process corn.
The subsidies are generally to have spare production capacity, so as to reduce the risk of famine that can occur from the capitalistic incentives of optimising the system for efficiency above resilience.
(Not that the subsidies are always actually the most sensibly set out: but the general idea of subsidizing farming is an important one)
> The subsidies are generally to have spare production capacity
Maybe originally, but not anymore. Exhibit A: See America's waistline and the reason behind it (hint: farm subsidies and SNAP, two sides of the same coin).
Elevated hs-CRP roughly doubles your risk of heart disease. Here's a few things people do to lower it:
* Eat anti-inflammatory foods (e.g., blueberries) or use cooking techniques that produce fewer PAHs (e.g., braising or steaming rather than sauteing or broiling)
* Drink less alcohol
* Medications (e.g., statins and GLP-1s also have anti-inflammatory benefits)
Bad guess, I am not sure what OP really intends (perhaps you don’t consume whilst you sleep?!) because as you probably are starting to remember from primary school your body maintains homeostasis by continually respiring. It doesn’t suddenly decide to take a dump.
Ok, it does, but even when it does that, in order to do that it has been continually maintaining homeostasis
There is no issue with countries buying us treasuries. They sail off shelves. Until the current administration started to make it look like there’s a possibility that the country may bankrupt itself, which threw a risk component into US debt for like the first time ever
I think the real risk isn't USA going bankrupt as much as the dollar losing significant value relative to other currencies, thereby making holding US debt a bad deal for overseas holders, and/or possibility that Trump could do something previously unthinkable such as stopping interest payments on debt or trying to "make a deal" and renegotiate payments in some way.
The rubisco enzime is specially ineficient. While most enzimes can usually do thousands of reactions per second, rubisco does up to 10. Organisms compensate making loads of copies, to the point it's the most abundant enzime in nature.
What can a molecule do for such a long time? I mean they move very fast, the distances there is very short, so I kinda assumed that all the molecules do they do almost instantly. But 0.1 sec doesn't seem like an instant event.
I extremely dislike the way it goes forth and bolts. I don’t trust these tools enough to just point it in the direction and say go, I like to be a human in the loop. Perhaps the use case I was working on then was difficult (quite old react native library upgrade across a medium sized codebase) but I eventually cracked this on Claude; cursor in both entropic and Gemini left me with an absolute mess.
Even repeatedly asking the prompt to keep me in the loop it kept on just running haywire.
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